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胃癌中CDK6 mRNA表达变化研究 被引量：1

The Expression of CDK6 mRNA in Gastric Cancer
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摘要 目的探讨胃癌中CDK6 mRNA含量的变化。方法采用实时荧光定量PCR检测胃癌及癌旁组织中CDK6 mRNA的表达。结果胃癌组织中CDK6 mRNA含量为0.433±0.468,癌旁组织为1.304±1.206,两组相比,差异具有统计学差异(P<0.05)。结论 CDK6 mRNA在胃癌癌旁组织表达水平明显高于癌组织。 Objective To explore the expression of CDK6 mRNA in gastric cancer. Methods The expression of CDK6 mRNA was detected by real-time fluorescence quantitative PCR with GAPDH as an internal reference. Results The expression of CDK6 mRNA was 0.433 ±0.468 in gastric cancer tissues and 1 .304±1 .206 in normal adjacent tissues respectively.It was statistically significant between gastric cancer tissues and normal adjacent tissues （P〈0.05 ）. Conclusion The expression of CDK6 mRNA is higher in normal adjacent tissues of gastric cancer than that in cancer tissues.
作者 潘新民 徐国辉 秦豪杰 高林波 张林
机构地区 河南科技大学法医学院 四川大学华西第二医院 四川大学华西基础医学与法医学院
出处 《河南科技大学学报（医学版）》 2014年第2期81-83,共3页 Journal of Henan University of Science & Technology:Medical Science
基金 国家自然科学基金项目(81302149) 河南省科技厅自然科学基金项目(132300410105)
关键词 胃癌 CDK6 实时荧光定量PCR gastric cancer cyclin dependent kinases 6 real-time fluorescence quantitative PCR
分类号 Q754 [生物学—分子生物学] R735.2 [医药卫生—肿瘤]
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参考文献22

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河南科技大学学报（医学版）
2014年 第2期

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