摘要
目的 :研究垂体腺瘤患者血浆和肿瘤组织中的神经肽Y(NPY)浓度与垂体腺瘤的关系。方法 :放射免疫分析方法测定 3 3例垂体腺瘤组织和 2 0例病人血浆的NPY浓度。结果 :不同类型垂体腺瘤组织中NPY含量有显著差别 ,侵袭性垂体腺瘤NPY含量高于非侵袭性垂体腺瘤。肿瘤组织与血浆NPY水平呈正相关。结论 :不同类型垂体腺瘤组织和血浆中NPY含量有显著差别 。
Aim:To investigate the plasma and tumor tissue neuropeptide Y (NPY) concentration in patients with pituitary adenoma in relation to tumor progression. Methods:Thirty three tumor tissues and twenty plasmas of NPY were measured by radioimmunoassay in the human pituitary adenomas. Results:There was a distinctive difference of the level of NPY in different type of pituitary tumor. The invasive group had a higher level of NPY than that of noninvasive group. The NPY level in pituitary tumor tissues has a positive relationship with that in plasma. Conclusion:There was a distinctive difference of the level of NPY in different types of pituitary tumor and plasma which can be taken as an indicator to evaluate the tumor invasive potential.
出处
《中国临床神经科学》
2001年第2期148-150,共3页
Chinese Journal of Clinical Neurosciences
关键词
垂体腺瘤
神经肽Y
放射免疫分析
侵袭性
pituitary adenoma neuropeptide Y radiommunoassay invasiveness