1Anfosso F,Chomiki N,Alessi MC,et al.Plasminogen activator inhibitor-1 synthesis in the human hepatoma cell line HEP G2: Metformin inhibits the stimulating effect of insulin[].The Journal of Clinical Investigation.1993
2Dunaif A,Graf M,Mandeli J,et al.Characterization of groups of hyperinsulinemia[].The Journal of Clinical Endocrinology.1987
3Gilkison C,Stuart CA.Assessement of patients with acanthosis nigricans skin lesion for hyperinsulinia, insulin resistance and diabetes[].Nurse Practitioner.1992
4Scheen AJ,Letiexhe MR,Lefebvre PJ.Short administration of metformin improves insulin sensitivity and android obese subjects with impaired glucose tolerance[].Diabetic Medicine.1995
5Landin K,Tengbom L,Smith U.Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors[].Journal of Internal Medicine.1991
6Cederholm J,Wibell K.Insulin release and peripheral sensitivity at the oral glucose tolerance test[].Diabetes Research and Clinical Practice.1990
7Taniguchi A,Nakai Y,Fukushima H,et al.Pathogenic factor responsible for glucose tolerance in patients with NIDDM[].Diabetes.1992
8Diamanti-Kandarakise E,Kouli C,Tsianateli T,et al.Therapeutic effects of metformin on insulin resistance and hyperandrogenism in polycystic ovary syndrome[].European Journal of Endocrinology.1988
3Jones KL, Arslanian S, Peterokova VA, et al. Effect of metformin in pediatric patients with type 2 diabetes: a randomized controlled trial. Diabetes Care,2002,25:89-94.
4Ten S, Maclaren N. Insulin resistance syndrome in children. Clin Endocrinol Metab ,2004,89:2526-2539.
5Burke JP,Hazuda HP,Hale DE,et al. A quantitative scale of acanthosis nigricans. Diabetes Care, 1999,22 : 1655-1659.
6Gilkison C, Stuart CA. Assessement of patients with acanthosis nigricans skin lesion for hyperinsulinia, insulin resistance and diabetes. Nurse Pract, 1992,17 : 26-32.
7Kay JP, Alemzadeh R, Langley G, et al. Beneficial effects of metformin in normoglycemic morbidly obese adolescents. Metabolism, 2001,50 : 1457-1461.
8Shubha S, Geoffrey RA, Louise AB, et al. Randomized, controlled trail of metformin for obesity and insulin resistance in children and adolescents: improvement in body composition and fasting insulin. Clin Endocrinol Metab,2006,91:2074-2080.
9Scheen AJ, Letiexhe MR, Lefebvre PJ. Short administ ration of metformin improves insulin sensitivity and android obese subjects with impaired glucose tolerance. Diabetic Medicine, 1995,12:985-989.
10Landin K, Tengbom L, Smith U. Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors. Intern Med, 1991,229 : 181-187.