摘要
对518例住院药疹的致病药物进行临床分析,引起或可能引起药疹的药物有20余类,致病药物中以抗感染药居首位,其他依次为解热镇痛药、抗痛风药、抗癫痫药、生物制品及消炎抗风湿药等。多形红斑型药疹是最常见的药疹类型,其次是荨麻疹型等。绝大多数致病药物所致的药疹以多形红斑型最多见,抗痛风药和抗癫痫药多引起重症药疹,呋喃唑酮、破伤风抗毒素、狂犬疫苗多引起荨麻疹型药疹。
Analysing the clinical data of 518in patients with drug eruption.It was f ound that there were about 20kinds of drugs in-volved.The allergic drugs were usually as follows:antibiotics,antife brile and antalgic,antigout agents,antiepilepsy agents,biological preparations,anti-inflammation a nd anti-rheumatic,in order.The typ e of erythema multiforme was the most common type in the drug eruptions,then urticaria type.Most allergic drugs produce eruption of erythema multiforme type.Antigout agents and antiepilepsy a-gents produce Steven-Johnson syndr ome.Furazolidone,tetanus antitoxin,rabies vaccine produce urticaria type.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2002年第1期11-12,共2页
Journal of Clinical Dermatology
关键词
药疹
致病药物
临床分析
发病率
drug eruption
allergic drugs
clin ical analysis