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正交实验筛选黄连水提工艺 被引量:7

Optimization of Process for Extraction of Coptis chinensis Franch by Orthogonal Design
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摘要 目的 :优选黄连最佳酸水提取工艺。方法 :采用正交试验法 ,以提取液中小檗碱含量为考察指标 ,对影响黄连提取工艺的因素进行了研究。结果 :实验设计因素中回流次数影响最为显著。结论 :黄连的最佳提取工艺为 2 %盐酸 ,12倍量水 ,回流 3次 ,每次 1.5 Objective: To optimize the conditions for the extraction of Coptis chinensis Franch. Methods: Conditions for the extraction were studied by orthogonal design guided by the content of total berberine present in the extract. Results: Significant effect was observed in 2 different experimental conditions. Conclusion: The optimum condition for the extraction of Coptis chinensis Franch was 2% HCl flowing 3 times, 1.5 h each with 12 times water of the quantity of C. chinensis Franch.
出处 《时珍国医国药》 CAS CSCD 2001年第11期982-983,共2页 Lishizhen Medicine and Materia Medica Research
关键词 黄连 小檗碱 提取工艺 正交实验 Orthogonal design Coptis chinensis Franch Berberine Extraction process
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