中西医结合治疗特发性膜性肾病临床观察

Clinical observation of idiot membranous nephropathy treated With integrated traditional Chinese and western medicine

目的 :观察中西医结合治疗特发性膜性肾病临床疗效。方法 :对 6 8例特发性膜性肾病随机分为对照组 32例 ,治疗组 36例 ;对照组单纯用强的松和环磷酰胺、潘生丁、洛丁新 ,治疗组在用上述西药同时辨证加用中药治疗 ,观察 3年～ 6年。结果 :对照组完全缓解率为 2 8.1% ,总缓解率为 6 5 .6 % ;治疗组完全缓解率为 5 5 .6 % ,总缓解率为 86 .2 %。治疗组完全缓解率和总缓解率明显优于对照组 ,两组比较P <0 .0 5 ,具有显著性差异。结论 :中西医结合是治疗膜性肾病的有效方法。

Objective:To observe the clinical effect of integrated traditional chinese and western medicine(TCM-WM)on idiopathic membranous nephropathy(IMN).Methods:Sixty-eight patients of the IMN were randomly divided into two groups ,36 cases of the TCM-WM group were treated with prednisone ,CTX,persantine.Lotensin and chinese herds according to differentiation of symptoms and signs and observed for three to six years,the other 32 cases in the control group were treated with predinison,CTX,persantine and Lotensin .Results: The complete or total remission rates of the treated group were 55.6% or 86.2%respectively,significantly superior to those of the control group (28.1%,65.6%,P<0.05).Conclusions: TCM-WM treatment is an effective therapy to IMN .