摘要
清半夏75%乙醇提取物ig5g/kg和15g/kg,能拮抗蓖麻油和番泻叶引起的小鼠腹泻,显著抑制醋酸所致小鼠腹腔毛细血管通透性亢进,明显减少二甲苯引起的小鼠耳壳肿胀,但对小鼠胃肠对墨汁的推进运动无明显影响。
Rhizoma pinelliae 15g/kg and 5g/kg ig reduced the purgative effects of castor oil and senna in mice.They inhibited the increased vascular permeability induced by ip 0.7% acetic acid,xyleneinduced swelling of mouse ear and carrageenininduced swelling of mouse planta.Rhizoma pinelliae did not affect the gastrointestinal transport of Chinese ink in normal mice.It is suggested that the antiinflammatory effect of Rhizoma pinelliae may be one of its mechanisms of the antidiarrheal effect.
出处
《中药药理与临床》
CAS
CSCD
1998年第2期29-31,共3页
Pharmacology and Clinics of Chinese Materia Medica
基金
国家自然科学基金
关键词
清半夏
止泻
抗炎
药理学
Rhizoma pinelliae
antidiarrheals
antiinflammatory agents