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高频B超与钼靶X线及不同生物学指标检测对诊断乳腺癌腋窝淋巴结转移准确性探讨 被引量:22

Diagnostic accuracy of high resolution B ultrasound and mammography and detection of various biological indices for diagnosis of axillary lymph node metastasis of breast cancer
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摘要 目的:探讨高频B超、钼靶X线摄影联合检测LOX、Ki-67、RSK4蛋白表达水平对诊断乳腺癌腋窝淋巴结转移准确性。方法:对2014年9月—2017年9月收治的80例经手术治疗、病理证实的乳腺癌腋窝淋巴结转移的患者临床资料进行回顾性分析,并结合血液样本进行生化检测,统计检测方法的准确性、敏感性及不同蛋白表达的相关性。结果:高频B超、钼靶X线摄影联合使用对诊断的准确性较两者单独使用明显提高。LOX、Ki-67、RSK4蛋白表达水平与乳腺癌腋窝淋巴结转移有关(P<0.05)。高频B超与钼靶X线摄影联合检查以及LOX、Ki-67、RSK4蛋白水平检测与病理检测结果吻合度均较高(均к>0.4,P<0.05)。结论:高频B超与钼靶X线摄影联合使用能提高诊断乳腺癌淋巴结转移的准确性,LOX、Ki-67、RSK4蛋白的表达可作为诊断腋窝淋巴结转移的参考指标。
出处 《中国普通外科杂志》 CAS CSCD 北大核心 2018年第11期1487-1490,共4页 China Journal of General Surgery
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