支气管热成形术在极重度支气管哮喘人群中的应用

Application of bronchial thermoplasty in extremely severe bronchial asthma

支气管热成形术是利用射频消融的原理,消融气道平滑肌从而治疗支气管哮喘(哮喘)的新技术。近年来,对于热成型术治疗重症哮喘患者的有效性和安全性已被多项临床研究证实。目前国内尚无指南来明确支气管热成形术的适用人群,仍沿用国外临床试验的标准,排除了极重度哮喘人群,但实际上这类患者却是临床上最需要接受治疗的人群。因此,需对纳入了极重度哮喘人群的临床研究作一回顾性分析,以评估在此类人群中使用支气管热成形术的疗效和安全性。

Bronchial thermoplasty is a new technique that ablate airway smooth muscle to treat bronchial asthma (asthma), with the principle of radiofrequency ablation.In recent years, the effectiveness and safety of bronchial thermoplasty for treatment of severe asthma patients have been confirmed by a number of clinical studies.At present, there has not a guideline to clarify the applicable population of bronchial thermoplasty in China, and we still use the standards of foreign clinical trials, excluding the extremely severe asthma population.However, these patients are the ones most in need of medical treatment.Thus, a retrospective analysis which includes clinical studies involving severe asthma patients is need to assess the effectiveness and safety of bronchial thermoplasty in these patients.