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T淋巴细胞增殖在实验性变态反应性脑脊髓炎发病中的作用 被引量：1

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摘要 目的　探讨T淋巴细胞增殖在实验性变态反应性脑脊髓炎 (EAE)发病中的作用。方法　观察Lewis大鼠主动EAE临床症状和T淋巴细胞增殖。结果　EAE临床发病过程中 ,T淋巴细胞增殖旺盛。结论　EAE时 ,活化的T淋巴细胞可以通过BBB进入CNS ,浸入CNS的淋巴细胞能产生破坏性的细胞因子TNF α及某些酶类 ,推测T淋巴细胞增殖活跃 ,在导致EAE发病过程中起着至关重要的作用。
作者 吕佩源 宋春风
机构地区 河北省人民医院神经内科 河北医科大学细胞生物学教研室
出处 《卒中与神经疾病》 2002年第2期114-115,共2页 Stroke and Nervous Diseases
关键词 多发性硬化 实验性变态反应性脑脊髓炎 淋巴细胞增殖
分类号 R744.51 [医药卫生—神经病学与精神病学]
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参考文献9

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同被引文献10

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卒中与神经疾病
2002年 第2期

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