脑梗死患者应用阿司匹林联合他汀类药物对颈动脉斑块的影响评价

The application of combing aspirin with statin to carotid plaques of cerebral infarction patients

目的探讨脑梗死患者应用阿司匹林联合他汀类药物对颈动脉斑块的影响。方法选自2011年6月-2013年6月本院诊治伴颈动脉斑块的脑梗死患者68例,按随机数字表方法分成两组,每组34例,予阿司匹林作对照组,予阿司匹林联合他汀类药物作研究组,分析两组疗效、颈动脉内膜-中层厚度(IMT)及颈动脉的斑块面积情况。结果研究组有效率97.06%,比对照组82.35%高,差异具统计学意义(P<0.05);同时两组治疗后IMT和颈动脉斑块面积均比治疗前少,比较差异明显(P<0.05);且治疗后研究组IMT和颈动脉斑块面积比对照组少,比较差异具统计学意义(P<0.05)。结论对伴有颈动脉斑块的脑梗死患者予阿司匹林联合他汀类药,能明显提升患者疗效,并改善颈动脉斑块症状,具有一定临床应用和研究价值。

Objective To explore application of cerebral infarction patients using aspirin combined statin effects on carotid plaques.Methods we chose the data in June 2011-June 2013 in our hospital for treatment of 68 patients with cerebral infarction with carotid plaques,these were divided into two groups according to random number table method, each group were 34 cases,we used aspirin for control group,and used aspirin combined statin drugs for experiment team,we had analysis of two groups of curative effect,carotid intima-media thickness and carotid artery plaque area.Results The experiment team＇s effectiveness was 97.06%,were higher than the control group of 82.35%,There were statistical significance difference（P 〈 0.05）;At the same time,the two groups after treatment of IMT and carotid plaque area were less than before treatment,compare the difference to be markedly （P 〈0.05）;And after the treatment team IMT and carotid plaque area is less than the control group,There were statistical significance difference （P 〈0.05）.Conclusion Cerebral infarction patients with carotid plaques were treated with aspirin combined statin drugs, patients could obviously improve,and improve the symptoms of carotid plaques,has certain clinical application and research value.