铁缺乏症婴幼儿认知水平研究

Analysis of iron deficiency infants' cognitive level

目的了解非贫血铁缺乏症和缺铁性贫血婴幼儿的认知水平,为进一步治疗提供科学依据。方法采用Gesell发育测试法评估非贫血铁缺乏症和缺铁性贫血婴幼儿适应性、大运动、精细动作、语言和个人社交5个能区发育水平。结果患铁缺乏症的男婴较女婴更多(χ2=13.06,P=0.001),非贫血铁缺乏症(non-anemia iron deficiency,NAID)组、缺铁性贫血(iron deficiency anemia,IDA)组较铁充足(iron sufficiency,IS)组婴幼儿的5个能区发育水平落后(F适应性=13.64;F大运动=6.24;F精细动作=6.25;F语言=4.89;F个人社交=9.14,P值均<0.01),NAID和IDA婴幼儿之间差异无统计学意义;但男性婴幼儿在语言和个人社交发育商分数较女婴更低(F=9.299,P=0.003;F=4.250,P=0.042)。结论铁缺乏症伴或不伴贫血对婴幼儿的认知水平都有影响,提示在临床工作中应早期干预铁缺乏。

Objective To analyse the non anemia iron deficiency（NAID） and iron deficiency anemia（IDA） infants＇ cognitive level. Method The Gesell developmental test was used to assess the development of adaptive behavior（A）,gross motor（G）,fine motor（F）,language（L）,personal-social behavior（P）. Results Both NAID and IDA groups＇ male infants were more than female ones（χ^2 = 13. 06, P= 0. 001 ） ; The mental developmental quotient （DQ） of NAID group and IDA group was lower than iron sufficiency （IS） group, but no difference between NAID group and IDA group（FA= 13.64, FG= 6.24, FF= 6.25, FL = 4.89, FP = 9.14, all P〈0.01 ） ; The male infants＇ developmental quotients（DQ） of language, personalsocial behavior were significantly lower than those of female infants（F=9. 299,P=0. 003;F=4. 250,P=0. 042）. Conclusion The DO of Iron deficiency with or without anemia infants are lower than iron sufficient ones, that means iron deficiency needs early intervention in clinic.