阿托伐他汀对急性脑卒中患者神经功能及日常生活能力的作用

Atorvastatin on Neurological Function and Activities of Daily Living of Patients with Acute Stroke

目的:观察阿托伐他汀治疗急性脑卒中患者的临床疗效,及对其神经功能与日常生活能力的作用。方法:选取2010年5月至2013年7月收治的急性脑卒中患者94例,随机分为观察组与对照组,对照组患者使用阿司匹林等进行常规治疗,观察组在此基础上加用阿托伐他汀联合治疗,对比观察两组患者临床疗效及对神经功能(NIHSS量表)、日常生活能力(ADL量表、BI指数)的影响。结果:观察组患者治疗显效率与总有效率明显高于对照组,P<0.05;治疗后两组患者的NIHSS评分水平降低、BI指数水平升高,且观察组患者改善程度更为显著,P<0.05,具有统计学意义。结论:在急性脑卒中的临床治疗中应用阿托伐他汀具有理想的临床疗效,能够有效改善神经功能缺损状况,提高患者的日常生活能力,具有更为理想的临床应用效果及价值。

To observe the clinical efficacy of atorvastatin on patients with acute stroke , and the function on neurological function and activities of daily living .Method：94 cases with acute stroke trea-ted in our hospital from May 2010 to July 2013 were selected and divided into two groups randomly：the ob-servation group and the control group .The control group was treated with aspirin , based on which the obser-vation group was treated with atorvastatin .And then observed the clinical efficacy and influence on neurologi-cal function （ NIHSS scale ） , activities of daily living （ ADL scale and BI index ） .Result：The evident effec-tive rate and the total effective rate of the observation group was evidently higher than those of the control group,P〈0.05.NIHSS score level of two groups reduced , BI index level increased , and the improvement de-gree of the observation group was more evident , P〈0.05,There＇s statistical significanct difference .Conclu-sion：Atorvastatin treating acute stroke not only has ideal clinical efficacy , but also can improve the neuro-logical impairment and improve the activities of daily living of patients , which has ideal clinical application effect and value .