^(18)F-FDGPET/CT显像对淋巴瘤诊断、分期及疗效评价价值探讨

Investigate the Value of ^(18)F-FDG PET/CT Imaging for lymphoma Diagnosis,Staging and Treatment Evaluation

目的:探讨18氟-氟代脱氧葡萄糖(18F-FDG)PET/CT对淋巴瘤诊断、分期和疗效的评价价值。方法:入选我院2008年1月至2013年1月收治的52例经手术病理证实为淋巴瘤的患者,均进行18F-FDG PET/CT检查,并与病理结果进行比较,评价诊断价值,治疗前后对比分期改变,评价疗效和改变治疗方案。结果:PET/CT诊断发现异常高代谢情况51例(98.1%),其对淋巴瘤检查的灵敏度为98.1%(51/52),诊断率与病理结果比较相当,差异无统计学意义(P>0.05),治疗后,11例(21.2%)完全恢复,PET/CT未见高代谢或肿大情况,3例(5.8%)临床分期上调,15例(28.8%)分期下调,其中15例(28.8%)改变治疗方案。结论:18F-FDG PET/CT对淋巴瘤诊断准确性高,在分期和疗效评价中具有重要意义,有助于准确分期并鉴别残余病变性质。

Objective： To investigate value of the fluorine -18- fluorodeoxyglucose （18F-FDG）PET/CT for lymphoma diagnosis, staging and treatment evaluation. Methods： 52 cases of confirmed by operation and pathology of lymphoma patients were treated from January 2008 to January 2013 in our hospital as the object of study, all underwent （18F-FDG）PET/CT examination, and compared with the pathological results, evaluated the value of diagnostic, and before and after the treatment stage change, to evaluate the efficacy and change of the treatment plan. Results： PET/CT diagnosis of abnormal high metabolism in 51 cases （98.1%）, the sensitivity for detecting lymphoma was 98.1% （51/52）, rate and pathological results of diagnosis is quite, there was no significant difference （P〉0.05）, after treatment, 11 cases （21.2%） recovered completely, no high metabolism or swelling was found by PET OR CT in 3 cases （5.8%）, clinical stage increased, 15 cases （28.8%） stage down, including 15 cases of （28.8%） to change the treatment. Conclusion： （18F-FDG）PET/CT on lymphoma diagnosis accuracy is high, has the vital significance in staging and evaluation of therapeutic effect, conduce to accurate staging and differential residual lesions.