柳氮磺胺吡啶联合微生态制剂治疗溃疡性结肠炎的临床研究

Clinical study of sulfasalazine combined with microecological preparations in the treatment of ulcerative colitis

目的：研究柳氮磺胺吡啶联合微生态制剂治疗溃疡性结肠炎的临床疗效。方法：选取2012年7月～2013年7月我院收治的溃疡性结肠炎患者36例（男性21例，女性15例）作为研究对象，均在我院接受治疗，实验组19例接受柳氮磺胺吡啶联合微生态制剂治疗，对照组17例接受单独柳氮磺胺吡啶治疗。根据患者治疗后临床症状、总有效率和不良反应比较两组治疗结果。结果：实验组和对照组相比，不良反应无明显差异，P〉0．05，无统计学意义。实验组总有效率达到100％，对照组总有效率76．47％。P〈O．05，差异有统计学意义。结论：柳氯磺胺吡啶联合微生态制剂治疗溃疡性结肠炎的方案效果显著，值得推广。

Objective： To study the clinical effects of sulfasalazine combined with microecological preparations in the treatment of ulcerative colitis. Methods： 36 patients with ulcerative colitis from 2012 July to 2013 July in our hospital were cases （male 21 cases, female 15 cases）as the re- search object, were treated in our hospital, which were divided into experimental group of 19 patients received sulfasalazine combined with Medilac-S treatment, 17 cases in the control group received single Liu nitrogen SULFAPYRIDINE treatment. According to the clinical symptoms of the patients after treatment, total effective rate and adverse reaction were compared between the two groups of treatment outcome. Results： compared to the experiment group and the control group, no significant difference, the adverse reaction of P〉O.05, no statistical significance. The experimental group total effectiveness 100%, the comparison group total effectiveness 76.47% P〈O.05, there was statistical significance. Conclusion： the effect of sulfasalazine combined with microecological preparations in the treatment of ulcerative colitis is significant, worthy of promotion.