脓毒症急性肾损伤的评价方法及临床意义

The evaluation methods and clinical applicability of septic acute kidney injury

急性肾损伤（ acute kidney injury ， AKI）是危重症患者常见并发症，它的发病因素很多，其中脓毒症是其重要病因，其发病率及病死率高。重视和加强脓毒症急性肾损伤（ septic acute kidney injury ， SAKI）的早期诊断、积极防治、逆转其发生和发展对改善预后具有重要意义。因此，掌握相关临床检查在SAKI中的诊断、危险分层、预后评估和指导治疗有十分重要作用。本文通过复习文献，回顾总结不同影像学、生理学检查及生物标志物在SAKI中的临床价值。

Acute kidney injury （ AKI） is a common complication of critical illness .While the etiology of AKI in critically ill patients is often multifactorial , sepsis has consistently been found an important contributing factor and has been associated with high attributable morbidity and mortality . Importance should be attached to the early diagnosis , prevention and reverse of the progression .As a result, it is of great importance to understand the value of these clinical examinations in the diagnosis , classification, prognosis and clinical management in SAKI .This review will summarize the physiological biomarkers , imaging examination and biological biomarkers in SAKI and their clinical applicability .