电子支气管镜下冷冻治疗支气管结核102例分析

Bronchial Tuberculosis by Cryotherapy under Electronic Bronchoscope: Analysis of 102 Cases

目的：探讨电子支气管镜下冷冻治疗支气管结核的疗效。方法2010年2月～2013年7月，对102例支气管结核在常规抗结核化疗基础上，在支气管镜介入下冷冻治疗2～6次，每次间隔2～3周。冷冻术后，用抗结核药物雾化吸入治疗。结果90例溃疡坏死型及肉芽增殖型治疗后，支气管黏膜光滑、管腔通畅；7例支气管腔内遗留少量瘢痕组织，轻度管腔狭窄，不影响通气功能；5例瘢痕型经多次冷冻治疗后，支气管腔狭窄程度无明显改变。治愈率88．2％（90／102），改善率6．8％（7／102），总有效率95．1％（97／102）。结论电子支气管镜下冷冻治疗支气管结核，创伤小，无明显并发症，安全有效。

Objective To observe the cryotherapy ’ s efficacy for bronchial tuberculosis under electronic bronchoscope. Methods A total of 102 cases of bronchial tuberculosis received cryotherapy under bronchoscope on the basis of conventional antituberculosis chemotherapy, ranging from 2 -6 times per case with an interval of 2 -3 weeks.After frozen surgery, inhalation therapy with anti-TB drugs was used. Results For 90 cases with necrotizing ulceration and granulation proliferative lesions, patients’ bronchial mucosa appeared smooth and the lumen became unimpeded.A small amount of scar tissue with mild stenosis was found in 7 patients’ bronchial lumen, but the ventilatory function was unaffected.Five cases of scar-type patients’ bronchial stenosis showed no significant change after repeated cryotherapy.Totally 88.2%（90/102） of the 102 cases were cured, 6.8%（7/102） improved, and the total efficiency was 95.1%（97/102）. Conclusion Cryotherapy under electronic bronchoscope for bronchial tuberculosis is a safe and effective method without significant complications.