应用丙泊酚联合帕瑞昔布钠对纤支镜检查患者实施无痛麻醉的效果分析

Analgesic anesthesia effect of application of propofol combined with parecoxib sodium in patients receiving bronchofiberscope examination

目的观察和分析对接受纤支镜检查患者应用丙泊酚联合帕瑞昔布钠进行无痛麻醉的临床效果。方法选取2012年1月-2014年2月在我院接受无痛纤支镜检查的患者87例为研究对象,随机分成A组、B组和C组。三组患者分别进行帕瑞昔布钠联合丙泊酚,丙泊酚联合芬太尼以及丙泊酚单独麻醉三种方式进行手术前麻醉,记录三个组各时刻MAP、SPO2变化情况、麻醉药物使用量及苏醒时间,并将结果制表分析。结果三组患者SpO2各个时刻都未出现明显变化,差异无统计学意义（P〉0.05）;三组患者纤支镜检查时间对比无显著性差异（P〉0.05）,A组麻醉药物使用量最少,且苏醒时间最短,较另外两组对比差异有统计学意义（P〈0.05）。结论在无痛纤支镜检查中,应用丙泊酚联合帕瑞昔布钠进行麻醉镇痛,对增加患者术后舒适感及术后生活质量有积极的作用。

Objective To observe and analyze the clinical analgesic anesthesia effect of propofol combined with parecoxib sodium for the patients receiving bronchofiberscope examination. Methods Eighty-seven patients receiving bronchofiberscope examination in our hospital from January 2012 to February 2014 were selected as the study subjects and randomly divided into group A, group B and group C. The three groups of patients received parecoxib sodium combined with propofol, propofol combined with fentanyl, and propofol respectively for preoperative anesthesia. The MAP and SPO2 changes, usage amount of anesthetic drugs, and awakening time of the three groups at different time were recorded,and the results were tabulated and analyzed. Results SpO2 of the three groups at different time did not change obviously, with no significant differences（P〉0.05）. The three groups did not have statistically significant differences in the bronchofiberscope examination time（P〉0.05）. Group A had the lowest usage amount of anesthetic drugs and the shortest awakening time, which had statistically significant differences to the other two groups（P〈0.05）. Conclusion In analgesic bronchofiberscope examination, the application of propofol combined with parecoxib sodium for anesthesia and analgesia plays a positive role in increasing the patients＇ postoperative comfort sensation and postoperative living quality.