摘要
为提高2,6-二羟基苯甲酸的合成收率,采用有机溶剂法制备了2,6-二羟基苯甲酸。探讨了溶剂种类,催化剂种类及用量,反应温度,反应压力及反应时间对产品收率的影响。确定以N,N-二甲基甲酰胺(DMF)为溶剂、K2CO3为催化剂,在140℃、10 atm压力下反应6 h,2,6-二羟基苯甲酸的单程收率可达35%以上,产品纯度95%以上。
In order to improve the yield of 2,6 - dihydroxy benzoic acid ,it was prepared in organic solvent. Effects of solvent type,catalyst type, reaction temperature, reaction pressure and reaction time on the yield were investigated. The best reaction conditionswere determined as follows： N,N-dimethyl formamide（DMF） is used as solvent, K2CO3 is used as catalyst, reaction temperature is 140℃,reaction pressure is 10 atm, reaction time is 6 h; Under above conditions, the yield of 2,6 - dihydroxy benzoic acid can reach to35%,the purity of 2,6 - dihydroxy benzoic acid can reach to 95%.
出处
《辽宁化工》
CAS
2014年第11期1387-1389,1426,共4页
Liaoning Chemical Industry
