超声心动图对妊娠期糖尿病胎儿心脏功能的评价

Echocardiography evaluation of fetal cardiac function in pregnant women with gestational diabetes mellitus

目的:探讨超声心动图在评价妊娠期糖尿病(gestational diabetes mellitus,GDM)胎儿心脏构型和功能变化中的价值。方法:对31例GDM胎儿(观察组)和35例健康孕妇胎儿(对照组)进行心脏结构和功能相关指标测定,并行组间比较。结果:观察组胎儿左心室厚度、右心室舒张末期内径、右室收缩末期内径、右心室壁的厚度、室间隔收缩末期厚度、左室射血分数、左室及右室短轴缩短率测定值均大于对照组,二尖瓣、三尖瓣E峰和A峰的速度比值均小于对照组,差异有统计学意义(P<0.05);2组胎儿左室舒张、收缩末期内径及室间隔舒张末期厚度测定值比较,差异均无统计学意义(P>0.05)。观察组胎儿左右心室Tei指数均明显大于对照组(P<0.05)。结论:GDM胎儿心脏构型和功能多发生变化,多普勒超声是评价这种变化的有效方法。

Objective：To study the value of echocardiography in the evaluation of changes of cardiac structure and function in gestational diabetes mellitus （GDM） fetuses. Methods：Indicators of cardiac structure and function of 31 gestational diabetes fetuses（observation group） and 35 fetuses of healthy pregnant women （control group） were measured, and compared between groups. Results：The measured value of left ventricular wall thickness,right ventricular diastolic diameter,right ventricular end systolic, right ventrieular wall thickness,inter-ventricular septum end-stolic thickness,left ventricular ejection fraction,left and right ventricular fractional shortening in the observation group were greater than those of the control group, the velocity ratio of peak E and peak A of mitral valve,tricuspid valve （E/AMV and E/ATV） was less than the control group （P〈0.05）. There were no significant differences of fetal LVDd,LVDs and inter-ventricular septum end-diastolic thickness （IVSd） between two groups （P〈0.05）. Tel indexes of fetal left and right ventricular of the observation group were higher than those of the control group （P〈0.05）. Conclusion：Diabetic pregnancy fetuses have lower cardiac function,echocardiography is an effective method for assessing the change.