南北葶苈子的最新研究进展

Advances on Lepidii Semen and Descurainiae Semen

葶苈子为十字花科植物播娘蒿Descurainia sophia或独行菜Lepidium apetalum的干燥成熟种子,前者习称南葶苈子,后者习称北葶苈子。中医理论认为其能泻肺平喘,利水消肿,用于痰涎壅滞、咳喘痰多、喘息不得卧及水肿、悬饮、小便不利等,临床应用较广泛,该文从本草考证、品种鉴别、炮制研究、化学成分、药理作用、含量分析、毒性等方面就南葶苈子与北葶苈子近年来的研究进展进行综述,为其深入研究与开发提供参考。

＂Tinglizi＂, the ripe seed of Descurainia sophia and Lepidium apetalum, is a member of Brassicaceae （Cruciferae）. Traditionally, the former is called ＂Nantinglizi＂ （Descurainiae Semen） while the latter is called ＂Beitinglizi＂ （Lepidii Semen）. In the theory of traditional Chinese medicine, it has the power to purge lung-fire, relieve dyspnea, promote diuresis and reduce edema, and it is mainly indicated in a case with phlegm-fluid accumulation, cough with excessive sputum, dyspnea with being unable to lie, and general swelling. In view of its wide-spread application in clinic, a comprehensive review of Lepidii Semen and Descurainiae Semen was conducted from the following aspects： herbalogical study, variety identification, historical evolution of processing, chemical constituents, pharmacological effects, quantitative determination and toxicity which could provide reference for further research and development of ＂Tinglizi＂.