我院2013年门诊患者应用华法林的处方分析

Analysis of Warfarin Outpatient Prescriptions in Our Hospital in 2013

目的：为临床合理使用华法林提供参考。方法：对我院2013年门诊使用华法林的处方进行调查,统计分析患者年龄、临床诊断、用药科室以及联合用药情况。结果：共调查目标处方746张,患者中男性428例、女性318例,年龄18~95岁。涉及24个科室和29种临床诊断,有50张（6.7%）处方的诊断与用药不一致,555张（74.4%）处方采取了联合用药;联合用药涉及91种药品,可与华法林产生相互作用的有22种,占联合用药品种数的24.2%。结论：应进一步完善使用华法林处方的诊断录入,做到诊断与用药相符;慎重选择与华法林联用的药物。

OBJECTIVE： To provide reference for the rational application of warfarin in the clinic. METHODS： The warfarin outpatient prescriptions of our hospital in 2013 were analyzed statistically in respect of the age of patients, diagnosis, departments and drug combination. RESULTS： Totally 746 prescriptions were surveyed with 428 males and 318 females involved, including 24 departments and 29 diagnosis, and the age of patients were ranged from 18 to 95 years old. The diagnosis was inconsistent with the treatment in 50 prescriptions, and drug combination was found in 555 prescriptions, accounting for 6.7% and 74.4% respectively. There were 91 kinds of drugs used in combination with warfarin, of which, 22 kinds of drugs had interaction with warfarin, ac- counting for 24.2%. CONCLUSIONS： The warfarin prescriptions input should be further improved to make sure diagnosis consis- tent with treatment. In order to ensure safe and effective drug use, it is suggested to carefully choose the drugs to combine with war- farin.