早期帕金森病患者动态姿态平衡检查分析

Analysis of dynamic posture in patients with early Parkinson disease

目的运用动态姿态平衡仪对早期帕金森病患者进行姿势定量测试分析。方法选取H&Y分期不大于2的早期帕金森病患者32例,其中H&Y1期10例,1.5期9例,2期13例。同时设32例健康受试者作为对照组。运用Neuro Com灵巧动态姿态平衡仪及长平台评估对早期PD患者和健康受试者进行动态姿态平衡测试分析,测试内容包括感觉整合测试(sensory organization test,SOT)、运动协调性测试(motion coordination test,MCT)、适应性测试(adaptive testing,ADT)及步行测试。并对测试结果进行两组间的比较。结果早期PD患者SOT平均综合得分为64分,对照组为78分,经感受器分析,早期PD患者视觉、前庭觉的平衡比率均未达正常值,分别为(73.55±3.15);(45.25±4.25),与对照组比较明显降低,P值分别为0.037和0.021。在运动协调性测试中,早期PD患者重心位置异常率为70.3%,明显高于对照组(7%)。在适应性测试及步行测试中,早期PD患者表现异常率分别为33%和57%,而对照组均0%,差异具有显著统计学意义(P<0.001)。结论早期帕金森病患者已出现不同程度的姿势平衡障碍,早期姿势平衡评估,有利于针对性进行康复训练。

Objective To quantitatively analyze the dynamic posture in patients with early stage Pakinson disease （ESPD） by using dynamic posture equilibrium equipment. Method Thirty two ESPD patients were recruited in this study, in which, 10 was at Hoehn-Yahr stage 1, 9 at Hoehn-Yahr stage 1.5, 13 at Hoehn-Yahr stage 2. Thirty two age and gender matched healthy subjects served as a control group. The sensory organization test （SOT）, motion coordination test （MCT）, adaptive test （ADT）, walk across were performed in those two groups using NeuroCom smart dynamic posture equipment. Results The average composite scores for SOT were 64 and 79 in ESPD patients and control group（P=0.032）. The eqilibrium ratio of vision and vestibular sense were obviously lower in ESPD patients than in the control group （ 73.55±3.15 vs. 82.45±3.53, P=0.037;45.25±4.25 vs. 66.43±6.98, P=0.021）. MCT showed that ESPD patients had a higher abnormality ratio of centre-of-gravity position compared with controls （ 70.3%vs. 7% ）（P〈0.001）. ESPD patients had 33% and 57% abnormality in ADT and Walk Across, which were obviously higher compared with control group （P〈0.001）. Conclusions ESPD patients have different degrees of posture disorders and posture equilibrium assessment at early stage is beneficial to rehabilitation training.