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成纤维样滑膜细胞microRNA与类风湿关节炎 被引量:3

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摘要 类风湿关节炎(Rheumatoid arthritis,RA)是一种慢性、炎性、系统性疾病,以对称性多关节炎为主要临床表现,最终导致关节软骨、韧带、肌腱等组织和脏器损害,是人类丧失劳动力和致残的主要原因之一。目前RA的发病机制不是很明确,但环境因素、遗传易感性、免疫功能紊乱被认为与其关系密切。因此,明确RA的发病机理,早期、准确的诊断,对于采取治疗措施以控制病情的发展、避免不可逆的关节损伤是至关重要的。
作者 祝静 邢艳
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2015年第2期277-281,共5页 Chinese Journal of Immunology
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