盐酸溴己新葡萄糖注射液治疗小儿支气管肺炎的疗效

Curative Effect of Bromhexine Hydrochloride and Glucose Injection on Bronchial Pneumonia in Children

目的观察盐酸溴己新葡萄糖注射液治疗小儿支气管肺炎的疗效.方法将196例小儿支气管肺炎患儿按简单随机方法分为治疗组100例和对照组95例,2组抗生素及对症治疗方案基本相同,治疗组加用盐酸溴己新葡萄糖注射液0.1～0.2mg·kg^-1·d^-1静脉滴注,比较2组的疗效.结果与对照组比较,治疗组体温恢复正常,咳嗽消失,肺部湿音、哮鸣音消失,临床治愈时间均明显缩短（均P〈0.05）;治疗组总有效率明显高于对照组（93%比60%,P〈0.05）.结论盐酸溴己新葡萄糖注射液可有效治疗小儿支气管肺炎.

Objective To observe the curative effect of bromhexine hydrochloride and glucose injection on bronchial pneumonia in children.Methods A total of 196 children with bronchial pneumonia were randomly divided into treatment group(n=100)and control group(n=95).Chil-dren in both groups received the same antibiotic and symptomatic treatment.In addition,children in treatment group were intravenously given bromhexine hydrochloride and glucose injection(0.1-0.2 mg·kg-1 ·d-1 ).The curative effect was compared between the two groups.Results The time to body temperature returning to normal,time to cough disappearance,time to moist rale and wheezing rale disappearance,and time to clinical healing in treatment group were significantly shorter than those in control group(P < 0.05).Moreover,the total effective rate in treatment group was significantly higher than that in control group(93% vs 60%,P <0.05).Conclusion Bromhexine hydrochloride and glucose injection is effective for bronchial pneumonia in children.