波立维联合苦碟子治疗急性脑梗死的临床疗效观察

Therapeutic efficacy of associated application of polivy and herba patriniae extract injection for the patients with acute cerebral infarction

目的：探讨波立维联合苦碟子注射液治疗急性脑梗死的临床疗效。方法：选择我院2011—01-2013—01急性脑梗死患者138例，随机分为实验组和对照组，每组69例。两组患者均根据病情给予基本对症支持治疗，并严格控制血糖，血压等。在常规治疗基础上，实验组给予苦碟子注射液20ml加入5％葡萄糖注射液250ml，静脉滴注，1／d，同时给予波立维75mg，口服，1／d；对照组给予波立维75mg，口服，1／d。2周后观察两组患者血液学变化、临床疗效、神经损伤及不良反应。结果：2周后，实验组的临床疗效、神经损伤评分、血液学指标均优于对照组，差异有统计学意义（P〈O．05），在治疗过程中均无不良反应发生。结论：波立维联合苦碟子注射液治疗急性脑梗死可以有效改善急性脑梗死患者的血液流变学，提高急性脑梗死的临床疗效，有一定的临床应用价值。

Objective： To observe the therapeutic efficacy of associated application of polivy and herba patriniae extract injection for the patients with acute cerebral infarction. Methods： A total of 138 patients with cerebral infarction were randomly divided into polivy group and polivy plus herba patriniae extract injection group, 69 patients in each group. The patients in polivy group were treated with polivy at 75 mg/d for 2 weeks,while the patients in the other group were treated with herba patriniae extract injection 20 ml/d by intravenous infusion and polivy 75 mg/d for 2 weeks. All patients were observed and analyzed for the differences in the therapeutic effect score, the neurological deficit score and the adverse effects. Results： Polivy plus herba patriniae extract injection is superior to simple polivy in the therapeutic effect score and neurological deficit score （P 〈 0. 05）. Conclusion： The associated application of herba patriniae extract injection and polivy can improve the therapeutic efficacy and decrease the neurological deficit for the patients with acute cerebral infarction.