期刊文献+

复方甘草酸苷联合强的松片治疗OLP的临床观察 被引量:1

下载PDF
导出
摘要 目的:观察复方甘草酸苷片联合强的松片治疗口腔扁平苔藓的临床疗效。方法:将50例口腔扁平苔藓患者随机分为治疗组和对照组,每组25例。对照组给予口服强的松1mg/kg,3次/日;治疗组在对照组治疗基础上,口服复方甘草酸苷片50mg,3次/日。症状缓解后,药物均逐次减量至停药,疗程3个月,观察疗效。结果:治疗组治愈率32.00%,复发率16.00%;对照组治愈率12.00%,复发率36.00%。结论:复方甘草酸苷片联合强的松片治疗口腔扁平苔藓有较好的临床疗效,且复发率低。
作者 康靖
出处 《甘肃医药》 2015年第4期298-300,共3页 Gansu Medical Journal
  • 相关文献

参考文献5

二级参考文献19

  • 1周刚,刘宏伟,林梅,唐国瑶.口腔扁平苔藓(萎缩型、糜烂型)疗效评价标准(试行)[J].中华口腔医学杂志,2005,40(2):92-93. 被引量:372
  • 2周刚,樊明文,刘君炎.糖皮质激素对口腔扁平苔藓辅助性T细胞平衡的影响[J].中华口腔医学杂志,2005,40(2):98-101. 被引量:23
  • 3尚书,顾晶晶,唐国瑶.白芍总苷治疗口腔扁平苔藓的疗效评价研究[J].临床口腔医学杂志,2007,23(4):238-240. 被引量:22
  • 4史宗道.口腔临床药物学[M].3版.北京:人民卫生出版社,2008.
  • 5Sugerman PB, Savage NW, Walsh LJ, et al. The pathogenesis of oral lichen planus[J]. Crit Rev Oral Biol Med, 2002,13(4): 350 - 365.
  • 6Sinicrope FA, Ruan SB, Cleary KR, et al. bcl - 2 and p53oncoprotein expression during colorectal tumorigenesis [ J ].Cancer Res, 1995, 55(2): 237 - 241.
  • 7Zhou XJ, Sugerman PB, Savage NW, et al. Intra- epithelial CD8 + T cells and basement membrane disruption in oral lichen pla nus[J]. J Oral Pathol Med, 2002, 31(1): 23-27.
  • 8Shiavonnon A, Chrysomali E, Scorilas A, et al. TNF- α expression and apoptosis- regulating proteins in oral lichen planus: a comparative immunohistochemical evaluation [ J ]. J Oral Pathol Med, 2000, 29(5): 370-375.
  • 9Tseng Sc, Li Da, Ma X, et al. Suppression of transforming growth factor- beta isoforms, TGF- beta receptor type Ⅱ,and myofibroblast differentiation in cultured human corneal and limbal fibroblast by amniotic membrane matrix [ J]. J Cell Physiol, 1999, 179(3): 325 - 335.
  • 10Farhi D,Dupin N. Pathophysiology,etiologic factors,and clinicalmanagement of oral lichen planus, part I: facts and controver-sies [J]. Clin Dematol,2010,28(l) :100-108.

共引文献387

同被引文献13

  • 1周刚,刘宏伟,林梅,唐国瑶.口腔扁平苔藓(萎缩型、糜烂型)疗效评价标准(试行)[J].中华口腔医学杂志,2005,40(2):92-93. 被引量:372
  • 2Ryan K, Hegarty AM, Hodgson T. Aetiology, diagnosis and treat- ment of oral lichen planus [J]. Br J Hosp Med (Lond), 2014,75 (9) :492-496.
  • 3Popovska M, Grchevska L, Popovski V, et al. T-cell subpopulations in lesions of oral lichen planus [ J ]. Prilozi,2013,34 (2) :144-150.
  • 4Maehara T, Moriyama M, Kawano S, et al. Cytokine profiles contrib- ute to understanding the pathogenic difference between good syndrome and oral lichen planus: two case reports and literature review [ J ]. Medicine (Baltimore) ,2015,94 ( 14 ) : e704.
  • 5Lorenzini G, Viviano M, Chisci E, et al. A comparative immunohis- tochemical and immunophenotypical study on lymphocytes exp~ssion in patients affected by oral lichen planus [ J ]. J Oral Pathol Med , 2013,42 (8) :642-647.
  • 6Lee YC, Shin SY, Kim SW, et al. Intralesional injection versus mouth rinse of triamcinolone acetonide in oral lichen planus: a ran- domized controlled study [ J]. Otolaryngol Head Neck Surg, 2013, 148 ( 3 ) :443-449.
  • 7Arunkumar S, Kalappanavar AN, Annigeri RG, et al. Relative effi- cacy of pimecrolimus cream and triamcinolone acetonide paste in the treatment of symptomatic oral lichen planus [ J ]. Indian J Dent, 2015,6( 1 ) : 14-19.
  • 8朱三甫,胡姗姗.复方甘草酸苷的临床应用[J].安徽医药,2011,15(2):235-238. 被引量:34
  • 9金早蓉,秦念红,陈燕丹,方红辉.复方甘草酸苷治疗口腔扁平苔藓的临床疗效观察及免疫机制研究[J].齐齐哈尔医学院学报,2013,34(9):1276-1277. 被引量:7
  • 10蔡淦英,左雯鑫,李晓宇,陈艳卿.卡介菌多糖核酸局部注射治疗口腔扁平苔藓的疗效评价[J].海南医学,2014,25(8):1201-1203. 被引量:8

引证文献1

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部