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Prevention of febrile nonhemolytic transfusion reaction with leucocyte filtrated concentrates

Prevention of febrile nonhemolytic transfusion reaction with leucocyte filtrated concentrates
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摘要 Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration. Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration.
出处 《Journal of Medical Colleges of PLA(China)》 CAS 2002年第1期54-55,共2页 中国人民解放军军医大学学报(英文版)
关键词 leucocyte filtration febrile nonhemolytic transfusion reaction TRANSFUSION 白细胞过滤 发热性非溶血性输血反应 输血
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  • 1[1]Nielsen H J, Skov F, Dybkjacer E et al. Leucocyte and platelet-derived bioactive substances in stored blood: effect of prestorage leucocyte filtration[J]. Eur J Haematol, 1997;58(4) :273
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  • 3[3]Muller-Steihardt M, Schlenke P, Wagner T et al. Transfusion of platelet concentrates from pooled buffy-coats: comparison of bedside vs. prestorage leukofiltration [J]. Transfu Med, 2000; 10(1) :59
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