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白细胞过滤器滤除白细胞输血减少非溶血性发热性输血反应的临床研究 被引量:12

Clinical observation of reducing FNHTR by leucocyte filter dislodging white blood cells
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摘要 目的:观察应用白细胞过滤器滤除白细胞输血减少发热性非溶血性输血反应(FNHTR)的临床效果。方法:选择234例患者,按时间段和输血方式的不同将其分为过滤组和对照组。2013年1月至2014年7月采用白细胞过滤器输血的168例患者为过滤组;2011年5月至2012年12月采用普通一次性输血器直接输血的166例患者为对照组。观察比较两组患者FNHTR的发生率。结果:1过滤组输血后体温平均升高(0.46±0.67)℃,对照组输血后体温平均升高(1.38±0.79)℃,对照组体温升高值明显高于过滤组,两组差异比较有统计学意义(P<0.05);2过滤组发生FNHTR20例,发生率为11.11%,对照组发生FNHTR42例,发生率为27.81%,两组FNHTR发生率相比较,其差异有统计学意义(x2=14.90,P<0.01)。随着输血次数的增加,两组FNHTR发生率随之增高。结论:应用白细胞过滤器对临床输注用全血进行过滤可减少白细胞的输入,从而降低FNHTR的发生率,提高输血的安全性。 Objective: To observe the clinical effect of reducing FNHTR by Leucocyte filter dislodging WBC. Methods: One hundred and sixty-eight cases of patients with blood transfusion using leukocyte filter were chosen as filter group in Xianghe County People's Hospital from January 2013 to July 2014,166 cases of patients with blood transfusion using ordinary disposable apparatus as control group from May 2011 to December 2012. The incidences of FNHTR were observed and compared in two groups. The dates were analysed by using SPSS16.0 statistical software. Results:1)Average temperature rise after blood transfusion was (0.46+0.67)℃ in filter group, and was (1.38+0.79)℃ in control group, the difference was statistically significant (P〈0.05). 2)The incidence of FNHTR was 11.11% (20/168) in filter group, and was 27.81%(48/166)in control group, the difference was statistically significant (x^2=14.90, P〈0.01). With the increase of number of blood transfusions, the incidence of FNHTR increased subsequently in two groups. Conclusion: Blood transfusion filtered out white blood cells by using leucocyte filter could reduce the input of white blood cells, so as to reduce the incidence of FNHTR, improve the safety of blood transfusion.
出处 《中国医学装备》 2015年第4期97-100,共4页 China Medical Equipment
关键词 白细胞过滤器 滤除 白细胞 输血 非溶血性发热性输血反应 Leucocyte filter Filter White blood cells Blood transfusion Febrile nonhemolytic transfusion reaction
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