凉血解毒法内服外用治疗急性痛风性关节炎效果探讨

Discussion on treatment of acute gouty arthritis by internal and external method of cooling blood and detoxification

目的:探讨凉血解毒法内服外用治疗急性痛风性关节炎的临床效果。方法:选取我院自2012年6月—2014年6月收治的100例急性痛风性关节炎患者为研究对象。随机分为观察组与对照组,每组各50例。给予对照组口服双氯芬酸钠肠溶片治疗,给予观察组患者凉血解毒法内服外用治疗。对比两组的治疗效果。结果:1治疗7 d后两组BUA、ESR、CRP水平均得到明显改善,且与同组治疗前比较差异具有统计学意义(P<0.05)。而治疗后观察组的BUA、ESR、CRP降低水平均显著大于对照组,两组比较差异具有统计学意义(P<0.05)。2观察组治疗总有效率明显大于对照组(94.0%>74.0%);两组比较差异具有统计学意义(P<0.05)。3两组治疗后均未出现不良反应。结论:与传统西药治疗相比,凉血解毒法内服外用治疗急性痛风性关节炎的效果明显,可有效改善患者关节活动,提高患者生活质量,因此值得临床推广应用。

Objective：To investigate the clinical effect of internal and external method of cooling blood and detoxification in the treatment of acute gouty arthritis.Methods： 100 cases with acute gouty arthritis from June,2012 to June,2014 were selected and randomly divided into an observation group and a control group, 50 cases in each group.The control group was treated with diclofenac sodium enteric-coated tablets, while the observation group was treated with oral topical treatment of cooling blood detoxification method. The therapeutic effects of the two groups were compared. Results：1After 7 d of treatment, BUA,ESR,CRP levels were significantly improved, and the difference with the former treatment group was statistically significant（P〈0.05）. After treatment, BUA, ESR, CRP levels were significantly lower than those of the control group, and the difference was statistically significant（P 〈0.05）. 2The total effective rate of the observation group was significantly higher than that of the control group（94.0%〉 74.0%）; the difference was statistically significant（P 〈0.05）.3After treatment,no adverse reactions happened.Conclusion：Compared with Traditional Western Medicine treatment,the effect of cooling blood and detoxification method has more obvious effect on acute gouty arthritis. It can effectively improve the joint activities to improve the quality of life of patients, which is therefore worthy of clinical application.