有氧运动对心血管病高危因素新兵高强度军事训练后机体循环功能与应激反应的影响

Influence of Aerobic Exercise on Stress Response and Circulatory Function in Patients with High Risk of Cardiovascular Diseases after Intensive Military Trainings

目的观察有氧运动对存在心血管病高危因素新兵高强度军事训练后机体循环功能与应激反应的影响。方法选取某部存在心血管病高危因素的新入伍战士40名,在常规体能锻炼基础上增加有氧运动,为期2个月,于有氧锻炼开始前和结束后行10 km跑步运动应激测试,记录受试者运动应激前30 min及后10 min心率、收缩压、心率血压乘积的变化,以及血超敏C反应蛋白(hs-CRP)、心肌型肌酸激酶同工酶(CK-MB)和氨基末端脑钠肽前体(NTpro BNP)浓度的变化。结果受试者两次运动应激后心率、收缩压、心率血压乘积及血hs-CRP、NT-pro BNP浓度均升高(P<0.01);第2次运动应激后心率、心率血压乘积及血hs-CRP、NT-pro BNP浓度升高幅度低于首次运动应激后(P<0.05或P<0.01)。结论高强度军事训练可增加心血管病高危人群的应激反应并影响其循环功能,合理的体能锻炼联合有氧运动有助于减少急性心血管病事件甚至心源性猝死的发生。

Objective To observe the influences of aerobic exercise on stress response and circulatory function in the patients with high risk of cardiovascular diseases after intensive military training. Methods A comprehensive method was used including questionnaire survey, physical examination and 12-lead electrocardiogram. The population with cardiovascular high-risk （n = 40） was intervened by aerobic exercise for 2 months. The changes of HR, blood pressure, high-sensitivity C-reactive protein （hs-CRP） , creatinekinase-MB （CK-MB） and amino-terminal pro-B-type brain natriuretic peptide （NT- proBNP） were compared between the two groups before and after a 10 km run. Results There was no significant difference in rate-pressure product and biological indexes among two groups before the exercise. After the exercise, rate-pressure product, hs-CRR, and NT-proBNP increased and there was statistical difference between the two groups （P 〈 0. 05 or P 〈 0. 01 ）. Con- clusion The stress response and changes of circulatory function are significant in patients with high risk of cardiovascular dis- eases after an intensive military training. Aerobie exercise can inhibit this tendency and reduce the incidence rate of aeute car- diovascular events and even eardiogenic sudden death.