先天性心脏病合并肺炎患儿凝血功能的动态变化和临床意义

Dynamic Changes and Clinical Significance of Coagulation Function in Children with Congenital Heart Disease Associated with Pneumonia

目的探讨先天性心脏病合并肺炎患儿凝血功能的动态变化和临床意义。方法选取就诊有病情变化的先天性心脏病合并肺炎的患儿50例。重症期和好转期,比较两期PT、INR、Fib、TT值,统计学分析其差异性。结果重症期PT PT 19±2.5、INR 5.2±0.9、Fib 1.2±0.2、TT 13±1.9,好转期PT 8±2.1、INR 2.5±0.7、Fib 2.1±0.2、TT 6±1.6,两期比较,差异显著。结论先天性心脏病合并肺炎患儿随着病情变化,凝血功能也会出现变化,应引起重视。

Objective To investigate the dynamic changes of coagulation function and its clinical significance in patients with congenital heart disease complicated with pneumonia. Methods 50 cases of congenital heart disease complicated with pneumonia were selected and cases of the patients were selected..The difference of PT, Fib, INR and TT was statistically analyzed in the critical stage and the improvement period. Results The severe PT 19±2.5、INR 5.2±0.9、Fib 1.2±0.2、TT 13 ±1.9,Remission PT 8±2.1、INR 2.5±0.7、Fib 2.1±0.2、TT 6±1.6, the difference was significant. Conclusion The changes of the blood coagulation function in the patients with congenital heart disease complicated with pneumonia should be paid more attention.