尿毒症期肾移植受者术前血栓弹力图检测结果分析

Results of Thrombelastogram in Detection of Preoperative Renal Transplantation Receptors with Uremia

目的探讨血栓弹力图(TEG)在尿毒症期肾移植患者术前检测凝血功能中的意义。方法对2014年6—12月收治的尿毒症期肾移植受者126例(观察组)进行术前TEG检测,选择同期健康体检者(对照组)56例进行比较,分析尿毒症期肾移植患者术前凝血状况。结果观察组TEG的R值、K值均较对照组明显降低,α值较对照组明显增加(P<0.05),MA值两组比较差异无统计学意义(P>0.05)。观察组血小板计数少于对照组,活化部分凝血激酶时间短于对照组,MA值异常率高于对照组(P<0.05)。结论尿毒症期肾移植患者术前凝血功能紊乱且多变,TEG检测能较全面地反映凝血功能,为临床治疗和输血提供参考依据。

Objective To investigate the significance of thrombelastography（ TEG） in detection of preoperative coagulation function of renal transplantation receptors with uremia. Methods A total of 126 renal transplantation receptors with uremia（ observation group） from June to December 2014 were detected for preoperative TEG,and 56 healthy controls taking medical examinations at the same period were chosen as control group. The preoperative coagulation conditions of renal transplantation receptors with uremia were analyzed. Results Compared with those in control group,in observation group,the R and K values of TEG were significantly decreased,while α value was significantly increased（ P 0. 05）,and there was no significant difference in MA value in the two groups（ P 0. 05）. Compared with those in control group,in observation group,the value of blood platelet count was decreased,and activated partial thromboplastin time（ APTT） was shorter,and the abnormal ratio of MA value was higher than that in control group（ P 0. 05）. Conclusion The coagulation condition of preoperative renal transplantation receptors with uremia are disordered and changeable,and TEG detection can show comprehensive coagulation function so as to provide reference for clinical blood transfusion and treatment.