卵巢储备功能减退病因及处理

The etiology and treatment of diminished ovarian reserve

卵巢储备功能减退(DOR)病因复杂,涉及遗传学、手术、放化疗等医源性因素,环境及心理因素,其处理方法包括激素补充治疗(HRT)和不孕患者采用辅助生殖技术(ART)助孕,近年来应用脱氢表雄酮(DHEA)处理DOR也受到关注。

The etiology of diminished ovarian reserve （DOR） is complicated, which includes the genetic factor, iatrogenic factor, environmental and psycho- logical factor, and idiopathic factors. Hormone .re- placement therapy （HRT） and assisted reproduction technologies （ART） are the main treatment for DOR. Recently, the use of DHEA has been paid more at- tention in the DOR women. DOR reflects a process that accelerates the normal physiologic decline in ovarian function. Early diagnosis and treatment of DOR are very important in clinical practice in order to relieve the associated symptoms and improve the fertility of DOR patients.