中医治疗化疗后恶心呕吐研究进展

Progress in Research of TCM for Control of Chemotherapy-induced Emesis

恶心呕吐(CINV)是化疗药物引起的最常见、最严重的毒副作用及不良反应之一。频繁的恶心呕吐给患者造成极大的痛苦,也影响了治疗效果,并影响患者的身心健康,易使患者产生消极的情绪。对患者出现的不良反应管理不善可能导致患者的生活质量下降和依从性差,同时造成代谢紊乱、营养失调,甚至拒绝抗肿瘤治疗,减少其生存期。因此,积极、合理地预防和处理肿瘤治疗相关的恶心呕吐,是肿瘤顺利治疗的前提及保障。目前临床上应用的止吐药物虽见效快但副作用大,造成药物不良反应恶性循环。中医在治疗化疗后恶心呕吐方面取得了较明显的效果,就近几年来常用的中医治疗方法进行综述。

chemotherapy-induced nausea and vomiting（CINV）is one of the most common and serious side effects or adverse drugs reactions by chemotherapy drugs.A great many patients cannot suffer from the malaise of CINV which bring on wrench with therapy.The malaise has a physical and emotional effect on patients,and it can create negative feelings.Ineffective management of adverse events can lead to decreased patient quality of life during therapy,decreased treatment adherence.At the same time cause metabolic disorders,malnutrition,even refused to anti-tumor treatment,reduce patients＇ lifetime.Therefore,positive and reasonable prevention and treatment CLNV is the premise of successful treatment of the tumor and the guarantee.The current clinical application of antemesis drugs is effective but it had side effects,causing a vicious cycle of adverse drug reactions.The TCM in the treatment of CINV achieved obvious effects,the commonly used treatment of TCM in recent years were reviewed in this article.