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儿童特应性皮炎患者吸入物变应原过筛和食物变应原过筛检测结果和意义 被引量:3

Detection results of Phadiatop and Fx5E in children with atopic dermatitis and its significance
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摘要 目的了解乌鲁木齐地区特应性皮炎的相关过敏因素。方法入选乌鲁木齐地区1~14岁特应性皮炎患儿106例,分为婴幼儿组22例(≤3岁)及儿童组84例(〉3岁);应用固相免疫荧光法对入选者血清进行吸入物变应原过筛(Phadiatop)试验和食物变应原过筛(Fx5E)试验。结果所有患儿变应原检测总阳性率为80.19%,特异性免疫球蛋白E(sIgE)分级大于或等于3级阳性率为55.66%;Phadiatop试验sIgE分级大于或等于3级阳性率(48.11%)高于Fx5E试验(22.64%),差异有统计学意义(P〈0.05);儿童组Phadiatop试验sIgE分级大于或等于3级阳性率(54.76%)高于婴幼儿组(22.73%),而Fx5E试验sIgE分级大于或等于3级阳性率儿童组(17.86%)低于婴幼儿组(40.91%),差异均有统计学意义(P〉0.05)。结论变应原特别是吸入性变应原是乌鲁木齐地区特应性皮炎发病的重要因素,而3岁以下患儿变应原则以食物为主。 Objective To understand the related allergic factors of atopic dermatitis in Wulumuqi .Methods 106 patients with atopic dermatitis in Wulumuqi were included in this study and divided into the baby group (≤3 years old ,22 cases) and the child group(〉3 years old ,84 cases) according to age .The concentrations of serum Ph‐adiatop and Fx5E were measured by the solid‐phase immunofluorescence .Results The total positive rate of allergen detection in all children patients was 80 .19% ,the positive rate of sIgE grade≥3 was 55 .66% ;in the Phadiatop test , the positive rate of sIgE grade≥3 was 48 .11% ,which was higher than 22 .64% in the Fx5E test ,the difference was statistically significant (P〈0 .05);in the Phadiatop test of the child group ,the positive rate of the sIgE grade≥3 was 54 .76% ,which was higher than 22 .73% in the baby group ,but in the Fx5E results of the child group ,the positive rate of sIgE grade≥33 was 17 .86% ,which was lower than 40 .91% in the baby group ,the differences were statisti‐cally significant(P〉0 .05) .Conclusion Allergens especially inhaled allergens are the important factors of atopic der‐matitis in Wulumuqi area .But food is mainly allergen in children below 3 years old .
出处 《检验医学与临床》 CAS 2015年第17期2554-2555,共2页 Laboratory Medicine and Clinic
关键词 特应性皮炎 儿童 吸入物变应原过筛 食物变应原过筛 atopic dermatitis children phadiatop Fx5E
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