抗生素降阶梯疗法治疗老年重症肺炎的临床疗效分析

Clinical Effect of Antibiotic Therapy in The Treatment of Severe Pneumonia in Elderly Patients

目的：探讨抗生素降阶梯疗法在老年重症肺炎的临床疗效。方法从我院2011年6月～2015年6月我院收治的老年重症肺炎患者中随机抽取100例作为研究对象，按照随机数字表法将其分为研究组和对照组，每组各50例，给予研究组患者抗生素降阶梯疗法治疗，给予对照组患者一般抗生素治疗方法治疗，比较两组患者治疗效果、感染控制时间、平均机械通气（MV）时间以及住院时间。结果研究组患者治疗总有效率为96.00%，对照组患者治疗总有效率为74.00%，两组数据比较差异显著，有统计学意义（P＜0.01）；研究组患者感染控制时间、MV时间以及住院时间以及住院时间均明显短于对照组（P＜0.01）。结论对于老年重症肺炎患者，采用抗生素降价阶梯疗法相对传统治疗方法更有效。

Objective To investigate the clinical effect of antibiotic therapy in the treatment of severe pneumonia in elderly patients.Methods 100 case of elderly patients with severe pheumonia were randomly selected from June 2011 to June 2015 and divided into study group and control group, 50 cases in each group, giving study group with antibiotic deescalation therapy, given to the control group common antibiotics treatment, compared two groups of patients with treatment effect, infection control time, duration of mechanical ventilation （MV） time and hospitalization time. Results Study group total efficiency 96.00% compared with 74.00% of control group, the significant differences have statistical significance （P〈0.01）; infection of patients in the study group control time, the duration of MV and hospitalization time and hospital stay were significantly shorter than that of the control group （P〈0.01）.ConclusionThe use of antibiotic price escalation therapy relative to traditional treatment methods more effective,short time of hospitalization benefits.