普通外科围手术期抗菌药物合理使用及对策研究

Analysis of the utilization of antibiotic medicine in perioperative period of general surgery

目的 调查普通外科围手术期为预防手术部位感染使用抗菌药物的现状,分析评价其合理性,为进一步加强抗菌药物临床应用管理提供依据。方法 调查2012年11月-2014年12月普通外科除腹腔镜手术外的所有手术患者,分析评价手术患者围手术期抗菌药物使用存在的问题,并分析其与手术部位感染的相关性。结果 普外科抗菌药物预防性使用率为69.1%,I类切口手术用药不合理率高,预防用药时机不合理,且术后用药时间较长。发生手术部位感染28例,感染率为2.74%。结论 围手术期合理应用抗菌药物预防手术部位感染应掌握用药适应证、给药最佳时机和术后用药时间。

Objective To investigate the usage of antibiotic medicine in perioperative period of general surgery and evaluate if（ whether） antibiotic medicine was properly used,in order to improve the clinical application of antibacterial medicine. Methods All general surgeries except for laparoscopic surgeries operated from November 2012 to December 2014 were studied for the purpose of evaluating the application of antibiotic medicine in perioperative period and analyzing the correlation between the antibiotic medicine and surgical site infections. Results The prophylactic use rate of antibiotics on general surgeries in this hospital was 69. 1%. The indication rate of the use of type I incision surgery was high. The preventive medication timing was not proper and the antibiotic medicine was used for an unreasonably long time. Among all the cases,28 were infected and the infection rate was 2. 74%. Conclusion To prevent surgical site infection in perioperative period,such factors as indications,time to administer medicine and duration of administering medicine should be taken into consideration.