2型糖尿病患者合并无症状性菌尿临床特点分析

Clinical features of type 2 diabetic patients with asymptomatic bacteriuria

目的探讨2型糖尿病患者合并无症状性菌尿感染状况、菌谱特点及分布人群等临床特点,为临床工作提供参考。方法选取2012年5月至2013年7月期间收治的80例2型糖尿病患者合并泌尿系感染患者作为本组研究的观察对象,按照临床症状分为有症状组与无症状组各40例,分别取两组患者的清洁中段尿进行细菌培养、菌群鉴定及药敏试验,并分析其主要分布人群。结果 1革兰氏阴性杆菌(72.5%)是2型糖尿病合并泌尿系感染的最常见的病原菌,其中大肠埃希菌所占比例最大(52.5%),其次是表皮葡萄球菌(12.5%)、肺炎克雷伯菌(10%,4/40),两组病原菌分布构成比无明显差异。2人群分布:无症状组60岁以上患者占67.5%,女性患者占77.5%,均明显高于对照组。结论 2型糖尿病患者合并无症状性菌尿的临床发病率较高,发病人群以老年女性患者为主,在临床中应加强预防,根据细菌培养及药敏试验给予相应治疗。

Objective To investigate the clinical features of asymptomatic bacteriuria infection, bacteria spectrum char- acteristics and distribution of population and in patients with type 2 diabetes, to provide the reference for clinical work. Methods Totally 80 cases of patients with type 2 diabetes mellitus complicated with urinary tract infection patients dur- ing 2012 May to 2013 July were selected as the research object of observation, according to clinical symptoms were di- vided into symptomatic and asymptomatic groups 40 cases in each group, respectively, two groups of patients with clean urine in bacteria, fungi group identification and drug sensitive test, and analyze the main distribution of population. Re- suits ①Gram negative bacillus is a type 2 diabetes complicated with urinary tract infection is the most common patho- genic bacteria, including Escherichia coli accounted for the largest proportion, followed by Staphylococcus epidermidis, Klebsiella pneumoniae, two groups of pathogens distribution proportion had no obvious difference. ②The crowd distribu- tion ： the asymptomatic group of patients over 60 years of age accounted for 67.5%, female patients in 77. 5%. Conclu- sion Patients with type 2 diabetes with asymptomatic bacteriuria in clinical incidence, the incidence of senile female patients, in clinical prevention should be strengthened, according to bacterial culture and drug sensitive test to give cor- responding treatment.