银杏达莫对缺血性脑血管病患者血液黏度及血小板聚集率水平的影响

The effect of Ginkgo Leaf Extract and Dipyridamole Injection on blood viscosity and platelet aggregation of patients with ischemic cerebrovascular disease

目的研究银杏达莫对缺血性脑血管病患者血液黏度及血小板聚集率的影响。方法选取2011年5月-2013年5月医院缺血性脑血管病的患者158例。随机分为观察组与对照组各79例。对照组予复方丹参注射液静脉滴注,观察组予银杏达莫注射液,其他治疗条件均相同。4周后检测、比较2组患者血液黏度指标和神经功能缺损情况。结果治疗后观察组血液黏度与血小板聚集率均较对照组下降快,且观察组治疗后的神经功能缺损亦比对照组低,差异有统计学意义(P<0.05)。结论银杏达莫注射液不仅能明显减低患者血液黏度和血小板聚集率,还能有效降低神经功能缺损的评分,疗效好,安全性好,值得临床推荐。

Objective To study the effect of Ginkgo Leaf Extract and Dipyridamole Injection on blood viscosity and platelet aggregation rate of patients with ischemic cerebrovascular disease. Methods A total of 158 cases of patients with ischemic cerebral vascular disease from May 2011 to May 2013 in our hospital were selected and randomly divided into observation group and control group,each of 79 cases. The control group received compound Danshen injection for intravenous drip; the observation group was given with Ginkgo Leaf Extract and Dipyridamole Injection,the other conditions of 2 groups were the same. After four weeks,the blood standards and nerve function of 2 groups were compared. Results After the treatment,compared with the control group,the blood viscosity,platelet aggregation rate in the observation group declined faster,and the neurologic impairment of the treatment group were lower than that of the control group,the difference was statistically significant（ P 〈0. 05）. Conclusion Ginkgo Leaf Extract and Dipyridamole Injection can not only significantly reduce blood viscosity and platelet aggregation rate,but also effectively reduce the neurological deficit score,with good curative effect and security,which is worthy of recommendation.