脉络膜新生血管治疗的新进展

New progress in treatment for choroidal neovascularization

脉络膜新生血管见于许多眼部疾病,与视力下降密切相关。目前临床上脉络膜新生血管治疗常见的有手术疗法(如激光光凝,经瞳孔温热疗法及光动力学疗法)与药物疗法(如糖皮质激素、抗新生血管药物)。近年来,基因疗法、靶向治疗取得了一定的疗效,然而至今没有统一、确切的治疗方法。本文就脉络膜新生血管发病机制、手术治疗以及药物治疗方面的新进展行综述,为临床治疗提供参考。

The choroid neovascularization in many ocular diseases, is closely related to decreased vision. Current clinical choroid neovascularization common surgical treatments such as laser photocoagulation, the pupil thermotherapy and kinetics of light therapy, as well as medications such as corticosteroids, anti angiogenesis drugs, targeted gene thera- py in recent years, also have certain curative effect, but there is no unified, there is no special effective treatments. In this paper, the choroid neovascularization of pathogenesis, postoperative treatment and drug therapy were reviewed, pro- vide reference for clinical treatment.