中药内服外敷治疗急性痛风性关节炎的疗效观察

Efficacy observation on internal and external treatment of acute gouty arthritis by Traditional Chinese Medicine

目的:探讨四妙勇安汤煎汤内服兼如意金黄散外敷治疗急性痛风性关节炎的疗效观察。方法:将70例痛风急性发作患者随机分为对照组和治疗组各35例,对照组单纯予秋水仙碱口服治疗;治疗组采取四妙勇安汤煎汤内服兼如意金黄散外敷治疗。参照《中药新药临床研究指导原则》的相关疗效标准来评估疗效。结果:两组疗效比较(治疗组总有效率94.3%,对照组总有效率85.7%)及治疗前后尿酸比较治疗组前后差(305±68.2)μmol/L,对照组前后差(190±63.7)μmol/L均具有显著性差异(P<0.05)。提示治疗组疗效优于对照组。结论:四妙勇安汤煎汤内服兼如意金黄散外敷治疗急性痛风性关节炎的临床疗效值得肯定。

Objective： To observe the efficacy of Simiao Yong＇an Decoction internally combined with Ruyi Huangjin Powder externally in the treatment of acute gouty arthritis. Methods： 70 patients with acute gout attack were randomly divided into a control group and a treatment group, 35 cases in each group. Patients in the control group were treated with colchicine by oral administration; while patients in the treatment group were treated with Simiao Yong＇an Decoction internally combined with Ruyi Huangjin Powder externally. With reference to Guiding Principles of Clinical Research on New Medicines of Traditional Chinese Medicine, the curative effect was assessed. Results： The curative effects of the two groups were compared（ the total effectiveness of the treatment group was 94.3%, while that of the control group was 85.7%） and uric acid compared before and after the treatment（difference before and after the treatment group（305±68.2） μmol/L, the control group and（190±63.7） μmol/L had significant difference（P〈0.05）,which showed the efficacy of the treatment group was better than that of the control group. Conclusion： The clinical effect of Simiao Yong＇an Decoction internally combined with Ruyi Huangjin Powder has accurate effect.