多肿瘤标志物蛋白芯片检测系统在恶性肿瘤诊断中的应用

Multiple tumor markers protein chip detection system in the diagnosis of malignant tumor

目的探讨多肿瘤标志物蛋白芯片检测系统在恶性肿瘤诊断中的应用价值。方法选取在我院2012-01—2012—12行多肿瘤标志物蛋白芯片检测系统诊断的恶性肿瘤患者300例、其他良性疾病240例及健康体检者450例，比较血清中12种常见肿瘤标志物水平及诊断阳性率。结粜恶性肿瘤组患者阳性率87．0％、良性疾病组阳性率40．0％及健康体检组阳性率7．11％，差异有统计学意义，P〈0．05。结论在恶性肿瘤的临床诊断中，多肿瘤标志物蛋白芯片检测系统的敏感性高，适用于预后监测，可作为普查肿瘤常用方式，值得推广应用。

OBJECTIVE To investigate the value of multiple tumor marker protein chip detection system in diagno- sis of malignant tumor. METHODS In cancer patients who underwent multiple tumor marker protein chip detection sys- tem diagnosis of 300 cases, 240 cases of other benign diseases and healthy 450 cases, more of 12 common serum levels of tumor markers and diagnostic yield. RESULTS The positive rate of 87 % in patients with malignant group, the positive rate of benign disease positive rate of 40.0% and health examination group by 7.11 % enough to pay significant differ- ence （P〈0. 05）, with statistical significance. CONCLUSION The clinical diagnosis of malignancy, the multi-tumor marker protein chip detection system sensitivity is high, suitable for prognosis monitoring, can be used as a common means of census tumor, should be widely applied.