奥曲肽联合普萘洛尔治疗肝硬化上消化道出血临床疗效观察

Octreotide Combined Propranolol Treatment of Liver Cirrhosis Upper Gastrointestinal Hemorrhage Clinical Curative Effect Observation

目的观察应用奥曲肽联合普萘洛尔治疗肝硬化上消化道出血的临床疗效。方法回顾性分析自2011年10月~2015年5月收治的100例肝硬化上消化道出血患者的临床资料,随机分为观察组和对照组,每组各50例,对照组患者使用奥曲肽进行治疗,观察组患者联合应用奥曲肽和普萘洛尔进行治疗,观察两组患者的临床疗效。结果观察组的总有效率（92.0%）高于对照组的总有效率（76.0%）,两组差异有统计意义（P〈0.05）。结论奥曲肽联合普萘洛尔治疗肝硬化上消化道出血疗效好。

Objective To observe the application the octreotide combined propranolol clinical curative effect for the treatment of liver cirrhosis upper gastrointestinal bleeding. Methods Retrospective analysis from October 2011 to May 2015 were the clinical data of 100 patients with liver cirrhosis upper gastrointestinal bleeding, randomly divided into observation group and control group, 50 cases in each group, control group patients use the peptide treatment, observation group of patients with combined use of the peptide and propranolol treatment, to observe the clinical efficacy of two groups of patients. Results Observation group total effective rate（92.0%） than in the control group total effective rate（76.0%）, the difference between the two groups have statistical significance（P 0.05）. Conclusion The octreotide combined propranolol treatment of liver cirrhosis upper gastrointestinal hemorrhage curative effect is distinct.