脑桥出血早期患者脑皮层结构变化的MRI

Magnetic resonance imaging of structural change in the cerebral cortex for patients with early pons hemorrhage

目的：探讨脑桥出血早期患者大脑皮层结构变化，并分析与感觉运动功能损伤的相关性。方法：选择2014年5月～2015年3月我院接诊的16例脑桥出血患者作为观察组，选取同期16例健康者作为对照组。观察组患者人院后给予结构磁共振成像（MRI）检测，通过基于体素形态学方法对MRI的结构数据进行分析，比较其与健康者大脑灰质体积区域的改变。并分析其与运动感觉功能的关系。结果 两组受试者在年龄与性别方面比较差异无显著意义（P〉0．05）；观察组的轻触觉评分、针刺觉评分以及运动评分均低于对照组，两组比较差异有统计学意义（P〈0．001）；MRI结果分析显示，观察组的双侧初级感觉中枢、初级运动中枢及其辅助运动区发生了灰质体积减小的现象（P〈0．05）；观察组结构异常区域萎缩发生程度经相关分析与轻触觉评分、针刺觉评分以及运动评分无相关性（P〉0．05）。结论：与健康组比较，脑桥出血早期患者初级感觉中枢、初级运动中枢及其辅助运动区发生了灰质萎缩，但是萎缩程度与患者本身的轻触觉评分、针刺觉评分以及运动评分无关。

Objective. To evaluate the structural change in the cerebral cortex for early pons hemor- rhage patients and analysis sensory motor function lmPairement. Methods： 16 patients with pontine hem- orrhage from May 2014 - March 2015 in our hospital were selected as Observation Group. Mean while 16 healthy people served the control group. After admission, to the hospital the structure of magnetic reso- nance in observation group was detected and the data of voxel morphology structure of magnetic reso- nance in the two groups were compared about the change in brain gray matter volume area. And the corre- lation analysis of structural changes in the patients with cerebral cortex and the relationship between the sensorimotor functions. Results：There was no significant difference in the 2 groups about age and sex （P〈 0.05）; The light touch of a grade, acupuncture and sports scores in observation group were lower than those in the control group,and there was statistically significant （P〈0. 001） ; Based on voxel morphology analysis,observation group, in the of gray matter volume （P〈0.05） in bilateral primary sensory center, primary motor and its auxiliary motor area; the structure abnormal area shrink was not correl aed with light touch grade, acupuncture and sports scores（P〈0.05）. Conclusion：There exists gray matter in patients with pons hemorrhage in primary feeling center, the prirrary sports center and the supplementa- ry motor area,but there is no relationship of light touch grad, e, ：acupuncture, and sports scores.