药学干预对抗生素临床合理应用的影响分析

Effect Analysis of Pharmaceutical Intervention on the Rational Use of Antibiotics

目的探讨药学干预对于临床抗生素应用的影响。方法随机选取2013年9月～2015年4月本院收治的住院及门诊患者360例，按照是否接受药学干预将其分为观察组和对照组。其中对照组患者仅接受常规抗生素治疗，观察组患者采用药学干预方案指导抗生素使用，对两组患者的抗生素应用情况及其感染发生情况进行观察分析。结果观察组患者的抗生素使用率、抗生素费用占整体医疗费用的比例均低于对照组患者，差异具有统计学意义（P〈0.05）。结论在临床抗生素的应用过程中实施药学干预，有利于推进抗生素的合理使用，对于降低医疗成本，减轻患者痛苦具有作用。

Objective To investigate impact of the clinical use of antibiotics for pharmaceutical intervention. Methods Randomly selected in September 2013 to April 2015 during inpatient and outpatient hospital treated 360 cases, according to whether or not to accept the pharmaceutical interventions were divided into observation group and control group. The control group patients received only conventional antibiotic treatment, the observation group were treated with pharmaceutical intervention program guided antibiotic use. Two groups of patients and infection were observed and analyzed. Results Patients of observation group, the antibiotic usage, antibiotic costs accounted for the overall medical costs were significantly lower than the control group of patients, the difference was significant （ P 〈 0.05 ） . Conclusion hnplementing pharmacy interventions on antibiotics will help promote the rational use of antibiotics, reducing health care costs, reduce suffering.