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临床药师主导慢病管理对改善2型糖尿病患者临床指标的前瞻性随机对照研究 被引量:33

A prospective randomized controlled study of clinical pharmacists led chronic disease management to improve clinical indicators in patients with type 2 diabetes
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摘要 目的:通过前瞻性随机对照研究,对临床药师利用慢病管理模式改善2型糖尿病患者临床指标(血糖、血压、血脂)的效果进行分析。方法:纳入2型糖尿病患者共49例,住院期间所有患者接受相同治疗,出院时依据分配隐藏原则将患者随机分为干预组(26人)和对照组(23人)。出院后临床药师对干预组患者进行定期随访,根据患者临床指标改善治疗方案,进行持续的糖尿病教育,监测不良反应。出院3个月后两组患者均复查临床指标(糖化血红蛋白、低密度脂蛋白、收缩压)。结果:干预组的糖化血红蛋白达标率、低密度脂蛋白改善程度、收缩压改善程度等指标优于对照组(P<0.05)。结论:临床药师对2型糖尿病患者进行慢病管理可以提高临床治疗效果。 Objective: To evaluate the effects of chronic disease management led by clinical pharmacists on the clinical indexes(blood glucose, blood pressure, blood lipid) of patients with type 2 diabetes mellitus using a prospective randomized controlled study. Methods: The study included 49 patients with type 2 diabetes. All patients received the same treatment in hospital. On the principle of allocation concealment, the patients were randomly divided into intervention group(26 subjects) and control group(23 subjects) when discharged. Clinical pharmacists followed up the patients in the intervention group regularly, to improve the treatment plans according to the clinical indicators of the patients, to carry out continuous diabetes education to the patients, and to monitor adverse reactions. After 3 months, clinical indicators(glycosylated hemoglobin, low density lipoprotein, systolic blood pressure) of patients for the two groups were reviewed. Results: In the intervention group, the standard rate of glycosylated hemoglobin, the improvement of low density lipoprotein and systolic blood pressure were better than those of the control group(P 0.05). Conclusion: The chronic disease management led by clinical pharmacists can improve the clinical treatment effects of type 2 diabetes patients.
出处 《临床药物治疗杂志》 2015年第6期29-33,共5页 Clinical Medication Journal
基金 2014年北京药学会临床药学基金项目
关键词 2型糖尿病 慢病管理 临床药师 type 2 diabetes chronic disease management clinical pharmacists
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