阿托伐他汀治疗慢性硬膜下血肿的疗效分析

Effect analysis of atorvastatin in the treatment of chronic subdural hematoma

目的:探讨阿托伐他汀治疗慢性硬膜下血肿的临床疗效。方法:选取52例慢性硬膜下血肿患者随机分为观察组与对照组各26例,观察组患者口服阿托伐他汀治疗,对照组患者采用钻孔引流术治疗,随访12个月。结果:两组患者临床治疗总有效率均高于90%;两组患者治疗后ADL-BI评分均较治疗前有大幅提高,且观察组患者治疗后ADL-BI评分(64.3±6.4)高于对照组(57.4±6.2);症状消失时间(1.2±0.5)月长于对照组(0.6±0.3)月,差异有统计学意义(P<0.05);观察组患总并发症发生率(7.7%)、复发率(0%)均低于对照组患者(30.8%)和(23.1%),差异有统计学意义(P<0.05)。结论:阿托伐他汀治疗慢性硬膜下血肿患者,可以有效地提高患者生活质量,降低并发症与复发的发生风险,效果更佳。

Objective：To investigate the clinical effect of atorvastatin on chronic subdural hematoma.Methods：52 cases of chronic subdural hematoma patients were randomized into the observation group and the control group with 26 cases in each.Patients of the observation group were treated with atorvastatin,while patients in the control group were treated with trepanation and drainage,and had been followed up for 12 months.Results：The total clinical effective rate of both groups was higher than 90%.After the treatment,the ADL-BI score of two groups were significantly improved,and the ADL-BI score of the observation group（64.3±6.4）was higher than that of control group（57.4±6.2）,and the symptom disappearance time in observation group was（1.2±0.5）months,longer than（0.6±0.3）months in the control group（P〈0.05）.The total complication rate（7.7%）and recurrence rate（0%）in the observation group were lower than the repecitve 30.8% and 23.1% in control group（P〈0.05）.Conclusion：The application of atorvastatin to the treatment of patients with chronic subdural hematoma can effectively improve the life quality and reduce the risk of complications and recurrence.It is safe and effective for the long run.