丙泊酚静脉麻醉对老年患者心率和血糖变化的影响

Effect of Intravenous Anesthesia with Propofol on the Heart Rate and Blood Glucose Level in Elderly Patients

目的探析老年病人进行丙泊酚静脉麻醉对其血糖及心率的影响。方法选择该院2014年4月—2015年4月予以上腹部手术老年病人80例,根据随机数字表法分为研究组、对照组,每组40例,研究组进行丙泊酚静脉麻醉,对照组进行瑞芬太尼静脉麻醉法,比较两组围麻醉期不同时间点的心率及血糖水平变化情况等临床参数指标。结果研究组麻醉诱导前(T0)、给药后5 min(T1)、切皮后1 h(T2)、术毕(T3)的心率(HR)情况显著优于对照组,差异有统计学意义(P<0.05);研究组麻醉诱导前、给药5 min(T1)、切皮后1 h(T2)、术毕(T3)时段的血糖水平显著优于对照组,差异有统计学意义(P<0.05)。结论老年手术病人进行丙泊酚静脉麻醉,病人围手术期的心率及血糖水平变化平稳,效果确切,值得临床推广。

Objective To study the effect of intravenous anesthesia with propofol on the blood glucose level and heart rate （HR） in elderly patients. Methods 80 elderly patients underwent upper abdominal surgery in our hospital from April 2014 to April 2015 were selected and divided into the study group and the control group with 40 cases in each according to the random number table method. The study group were treated by intravenous anesthesia with propofol, and the control group were treated by intravenous anesthesia with remifentanil. And the HR and blood glucose level at different time points during anesthesia of the two＇ groups were compared. Results The heart rate of the study group was much better than that of the control group before anesthesia induction（T0）, 5min after administration（T1）, lh after skin incision（T2）, at the end of surgery （T3） with statistically significant differences（P〈0.05）. The blood glucose level of the study group was much better than that of the control group at T0, T1, T2, and T3 with statistically significant differences （/9〈0.05）. Conclusion For elderly patients un- dergoing surgery, intravenous anesthesia with propofol has exact effect, which can stabilize the perioperative heart rate and blood ~lucose level, so it is worthy of clinical promotion.