经皮椎体成形术后椎体压缩性骨折患者再骨折的危险因素分析

The risk factors of postoperative new vertebral compression fractures after percutaneous vertebroplasty

[目的]探讨经皮椎体成形术后椎体压缩性骨折患者再骨折的危险因素。[方法]回顾性分析2009年1月~2014年12月间在本院行经皮椎体成形术治疗的226例椎体压缩性骨折患者病例。依据是否发生再骨折,将患者分为骨折组（35例）和对照组（191例）。对两组患者相关因素进行单因素和Logistic回归分析。[结果]226例患者均顺利完成手术,术后1周VAS评分降低（P〈0.05）,随访6~36个月,35例（15.5%）患者发生新发骨折。单因素和Logistic回归分析显示：年龄、伤椎数、骨折病史、BMI、BMD、手术椎体数是患者出现再骨折的危险因素。[结论]椎体压缩性骨折患者行经皮椎体成形术后易发生再骨折,年龄、伤椎数、骨折病史、BMI、BMD、手术椎体数是出现再骨折的危险因素。

[Objective]To investigate the risk factors of postoperative new vertebral compression fractures after percutaneous vertebroplasty. [Method]A total of 226 patients with vertebral compression fractures from January 2009 to December 2014 treated by percutaneous vertebroplasty were retrospectively analyzed. Patients were divided into fracture group（ n = 35 cases）and control group（ n = 191 cases） based on with or without new fracture. The related factors were analyzed with univariate analysis and logistic regression. [Result]All 226 cases were successfully operated,and VAS scores after 1 week were significantly reduced compared with before surgery（ P 0. 05）. All patients were followed up for 6 to 36 months,35 cases（ 15. 5%） were found with new fractures. Univariate and logistic regression analysis results showed that age,vertebral fractures number,fractures history,BMI,BMD,and surgery vertebral fractures number were the risk factors for new vertebral compression fractures after percutaneous vertebroplasty. [Conclusion]Patients with vertebral compression fractures are easy to occur new vertebral compression fractures after percutaneous vertebroplasty,and age,vertebral fractures number,fractures history,BMI,BMD,and surgery vertebral fractures number are the risk factors for new vertebral compression fractures after percutaneous vertebroplasty.